INDICATIONS

REBLOZYL (luspatercept-aamt) is indicated for the treatment of anemia without previous erythropoiesis stimulating agent use (ESA-naïve) in adult patients with very low- to intermediate-risk myelodysplastic syndromes (MDS) who may require regular red blood cell (RBC) transfusions.

REBLOZYL (luspatercept-aamt) is indicated for the treatment of anemia failing an erythropoiesis stimulating agent and requiring 2 or more red blood cell (RBC) units over 8 weeks in adult patients with very low- to intermediate-risk myelodysplastic syndromes with ring sideroblasts (MDS-RS) or with myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T).

REBLOZYL (luspatercept-aamt) is indicated for the treatment of anemia in adult patients with beta thalassemia who require regular red blood cell (RBC) transfusions.

REBLOZYL is not indicated for use as a substitute for RBC transfusions in patients who require immediate correction of anemia.

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SUPPORT AND RESOURCES: HCP AND PATIENT RESOURCES

REBLOZYL resources

MDS patient leave-behind thumbnail MDS patient leave-behind thumbnail

MDS Target Patient Leave-Behind

Learn how switching to REBLOZYL immediately after ESA failure may help your patients.

Download Leave-Behind
MDS pathology checklist thumbnail MDS pathology checklist thumbnail

MDS Pathology Checklist

Information on how to collaborate with your pathologist to accurately diagnose your patients with MDS-RS.

Download Checklist
ESA failure video thumbnail ESA failure video thumbnail

Treating patients with REBLOZYL after ESA failure

Follow Dr De Castro as he discusses his clinical experience of switching to REBLOZYL after ESA failure.

Watch Video
Dosing calculator thumbnail Dosing calculator thumbnail

MDS Dosing Calculator

An online tool to help calculate the appropriate REBLOZYL dose for your patients with MDS-associated anemia.

Launch Calculator
MDS dosing flashcard thumbnail

MDS Dosing Flashcard

Clear and detailed guidance on dosing REBLOZYL to optimize response in patients with MDS-associated anemia.

Download Flashcard
MDS dosing and reconstitution guide thumbnail MDS dosing and reconstitution guide thumbnail

REBLOZYL MDS Dosing and Reconstitution Guide

How to dose and administer REBLOZYL to patients with MDS-associated anemia.

Download Guide
Clinical dosing video thumbnail

Clinical Dosing Experience

Learn more about Dr De Castro’s experience with REBLOZYL.

Watch Video
REBLOZYL® dosing and titration guide video thumbnail REBLOZYL® dosing and titration guide video thumbnail

Dosing and Titration with REBLOZYL

Watch a step-by-step video demonstrating the dosing and titration of REBLOZYL.

Watch Video
How to order REBLOZYL brochure thumbnail

How to Order and Access REBLOZYL Brochure

Find helpful information about ordering REBLOZYL.

Download Brochure
REBLOZYL® reimbursement and coding guide thumbnail

Reimbursement and Coding Guide for REBLOZYL

A guide with important coding, billing, and reimbursement information to support practice administrators and providers.

Download Guide
Beta Thalassemia dosing flashcard thumbnail

Beta-Thalassemia Dosing Flashcard

Clear and detailed guidance on dosing REBLOZYL to optimize response in patients with beta-thalassemia.

Download Flashcard

MDS patient brochure thumbnail

REBLOZYL MDS Patient Brochure


(In English or Spanish)

A guide for patients living with MDS-RS–associated anemia to learn more about REBLOZYL.

Download English Brochure
Download Spanish Brochure
MDS patient education brochure thumbnail

MDS Education Brochure

Give this brochure to your patients and caregivers so they can learn more about MDS, MDS-associated anemia, and support for people living with MDS.

Download Brochure
MDS patient website thumbnail

MDS Patient Website

An information-filled resource where MDS patients can sign up for information about REBLOZYL.

View Patient Site
REBLOZYL treatment tracker thumbnail

REBLOZYL Treatment Tracker

A tool to help you track your transfusions and communicate your symptoms to your healthcare team.

Download Tracker
Beta Thalassemia patient brochure thumbnail

REBLOZYL Beta-Thalassemia Patient Brochure

A guide for patients living with beta-thalassemia–associated anemia to learn more about REBLOZYL.

Download Brochure
Beta Thalassemia patient website thumbnail

Beta-Thalassemia Patient Website

An information-filled resource where patients with beta-thalassemia can sign up for information about REBLOZYL.

Visit Patient Site
Drip bag icon

REBLOZYL limits transfusions in patients with MDS-associated anemia1

Drip bag icon

REBLOZYL reduces transfusion burden in patients with beta-thalassemia1

SUPPORT AND RESOURCES: HCP AND PATIENT RESOURCES

REBLOZYL resources

MDS patient leave-behind thumbnail MDS patient leave-behind thumbnail

MDS Target Patient Leave-Behind

Learn how switching to REBLOZYL immediately after ESA failure may help your patients.

Download Leave-Behind
MDS pathology checklist thumbnail MDS pathology checklist thumbnail

MDS Pathology Checklist

Information on how to collaborate with your pathologist to accurately diagnose your patients with MDS-RS.

Download Checklist
ESA failure video thumbnail ESA failure video thumbnail

Treating patients with REBLOZYL after ESA failure

Follow Dr De Castro as he discusses his clinical experience of switching to REBLOZYL after ESA failure.

Watch Video
Dosing calculator thumbnail Dosing calculator thumbnail

MDS Dosing Calculator

An online tool to help calculate the appropriate REBLOZYL dose for your patients with MDS-associated anemia.

Launch Calculator
MDS dosing flashcard thumbnail

MDS Dosing Flashcard

Clear and detailed guidance on dosing REBLOZYL to optimize response in patients with MDS-associated anemia.

Download Flashcard
MDS dosing and reconstitution guide thumbnail MDS dosing and reconstitution guide thumbnail

REBLOZYL MDS Dosing and Reconstitution Guide

How to dose and administer REBLOZYL to patients with MDS-associated anemia.

Download Guide
Clinical dosing video thumbnail

Clinical Dosing Experience

Learn more about Dr De Castro’s experience with REBLOZYL.

Watch Video
REBLOZYL® dosing and titration guide video thumbnail REBLOZYL® dosing and titration guide video thumbnail

Dosing and Titration with REBLOZYL

Watch a step-by-step video demonstrating the dosing and titration of REBLOZYL.

Watch Video
How to order REBLOZYL brochure thumbnail

How to Order and Access REBLOZYL Brochure

Find helpful information about ordering REBLOZYL.

Download Brochure
REBLOZYL® reimbursement and coding guide thumbnail

Reimbursement and Coding Guide for REBLOZYL

A guide with important coding, billing, and reimbursement information to support practice administrators and providers.

Download Guide
Beta Thalassemia dosing flashcard thumbnail

Beta-Thalassemia Dosing Flashcard

Clear and detailed guidance on dosing REBLOZYL to optimize response in patients with beta-thalassemia.

Download Flashcard

MDS patient brochure thumbnail

REBLOZYL MDS Patient Brochure


(In English or Spanish)

A guide for patients living with MDS-RS–associated anemia to learn more about REBLOZYL.

Download English Brochure
Download Spanish Brochure
MDS patient education brochure thumbnail

MDS Education Brochure

Give this brochure to your patients and caregivers so they can learn more about MDS, MDS-associated anemia, and support for people living with MDS.

Download Brochure
MDS patient website thumbnail

MDS Patient Website

An information-filled resource where MDS patients can sign up for information about REBLOZYL.

View Patient Site
REBLOZYL treatment tracker thumbnail

REBLOZYL Treatment Tracker

A tool to help you track your transfusions and communicate your symptoms to your healthcare team.

Download Tracker
Beta Thalassemia patient brochure thumbnail

REBLOZYL Beta-Thalassemia Patient Brochure

A guide for patients living with beta-thalassemia–associated anemia to learn more about REBLOZYL.

Download Brochure
Beta Thalassemia patient website thumbnail

Beta-Thalassemia Patient Website

An information-filled resource where patients with beta-thalassemia can sign up for information about REBLOZYL.

Visit Patient Site
Drip bag icon

REBLOZYL limits transfusions in patients with MDS-associated anemia1

Drip bag icon

REBLOZYL reduces transfusion burden in patients with beta-thalassemia1

Reference: 1. REBLOZYL [US Prescribing Information]. Summit, NJ: Celgene Corporation; 2022.

2007-US-2300019     04/2023