INDICATIONS

REBLOZYL® (luspatercept-aamt) is indicated for the treatment of anemia in adult patients with beta thalassemia who require regular red blood cell (RBC) transfusions.

REBLOZYL® (luspatercept-aamt) is indicated for the treatment of anemia without previous erythropoiesis stimulating agent use (ESA-naïve) in adult patients with very low- to intermediate-risk myelodysplastic syndromes (MDS) who may require regular red blood cell (RBC) transfusions.

REBLOZYL® (luspatercept-aamt) is indicated for the treatment of anemia failing an erythropoiesis stimulating agent and requiring 2 or more red blood cell (RBC) units over 8 weeks in adult patients with very low- to intermediate-risk myelodysplastic syndromes with ring sideroblasts (MDS-RS) or with myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T).

REBLOZYL is not indicated for use as a substitute for RBC transfusions in patients who require immediate correction of anemia.

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Beta Thalassemia icon

REBLOZYL provides substantial clinical benefit by reducing RBC transfusion burden1,2

RBC=red blood cell.

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Learn about beta-thalassemia–associated anemia

Discover how ineffective erythropoiesis can impact beta-thalassemia patients.

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REBLOZYL reduces transfusion burden1

The efficacy of REBLOZYL in patients with beta-thalassemia was demonstrated in the BELIEVE trial.

Dose titration icon

Optimize patient response through proper dosing1

REBLOZYL offers 2 dose levels for patients with beta-thalassemia. Learn how to titrate REBLOZYL to maximize clinical benefit.

RBC=red blood cell.

Beta Thalassemia icon

REBLOZYL provides substantial clinical benefit by reducing RBC transfusion burden1,2

RBC=red blood cell.

Syringe Icon

Learn about beta-thalassemia–associated anemia

Discover how ineffective erythropoiesis can impact beta-thalassemia patients.

Clipboard icon

REBLOZYL reduces transfusion burden1

The efficacy of REBLOZYL in patients with beta-thalassemia was demonstrated in the BELIEVE trial.

Dose titration icon

Optimize patient response through proper dosing1

REBLOZYL offers 2 dose levels for patients with beta-thalassemia. Learn how to titrate REBLOZYL to maximize clinical benefit.

RBC=red blood cell.

References: 1. REBLOZYL [US Prescribing Information]. Summit, NJ: Celgene Corporation; 2023. 2. Cappellini MD, Viprakasit V, Taher AT, et al. A phase 3 trial of luspatercept in patients with transfusion-dependent β-thalassemia. N Engl J Med. 20​20;3​8​2(13):12​19-12​31.